Table 4.
Risk of maternal and paternal preconception ICU stay on preterm birth and pregnancy loss.
| ICU days | All | Full term | PTB | Pregnancy loss | PTB vs. full term |
Pregnancy loss vs. full term |
||
|---|---|---|---|---|---|---|---|---|
| RR (95% CI) | P trend | RR (95% CI) | P trend | |||||
| Mother | ||||||||
| 0 | 999,211 | 733,667 (73.4) | 51,717 (5.2) | 213,827 (21.4) | Ref. | 0.002 | Ref. | <.0001 |
| 1 | 592 | 346 (58.5) | 35 (5.9) | 211 (35.6) | 1.27 (0.83–1.71) | 1.88 (1.56–2.20) | ||
| ≥2 | 83 | ≥30 (44.6) | <11 (8.4) | 39 (47.0) | 2.32 (0.44–4.20) | 2.83 (1.58–4.08) | ||
| Father | ||||||||
| 0 | 999,172 | 733,614 (73.4) | 51,715 (5.2) | 213,843 (21.4) | Ref. | 0.02 | Ref. | <.0001 |
| 1 | 626 | 386 (61.7) | ≥30 (5.9) | 203 (32.4) | 1.24 (0.82–1.66) | 1.65 (1.37–1.94) | ||
| ≥2 | 88 | 50 (56.8) | < 11 (8.0) | 31 (35.2) | 1.73 (0.36–3.10) | 1.78 (0.98–2.57) | ||
Note: Percentages may not add to 100% owing to rounding. RRs adjusted for year of birth, maternal age, region of birth, and maternal factors including obesity, diabetes mellitus, hypertension, hyperlipidemia, and smoking. CI = confidence interval; ICU = intensive care unit; PTB = preterm birth; RR = risk ratio.