Table 2.
Comparison of laboratory parameters at admission between survivors and non-survivors.
| Total |
Survivor |
Non-survivor |
P value | |
|---|---|---|---|---|
| (n = 203) | (n = 145) | (n = 58) | ||
| Blood routine | ||||
| Leucocyte count (×109/L) | 6.2 (4.2–9.3) | 5.5 (3.9–7.5) | 8.9 (5.1–13.1) | <0.001 |
| Neutrophil count (×109/L) | 4.7 (2.9–7.9) | 3.7 (2.6–5.8) | 8.1 (4.4–11.8) | <0.001 |
| Lymphocyte count (×109/L) | 0.8 (0.5–1.2) | 1.0 (0.7–1.3) | 0.5 (0.4–0.7) | <0.001 |
| Coagulation function | ||||
| D-dimer (μg/ml) | 0.9 (0.5–2.7) | 0.6 (0.4–1.3) | 4.2 (1.1–27.0) | <0.001 |
| APTT (s) | 27.7 (24.7–32.2) | 27.6 (24.3–31.8) | 28.0 (24.8–33.7) | 0.50 |
| Prothrombin time (s) | 11.3 (10.4–12.2) | 11.1 (10.4–12.0) | 12.0 (10.3–13.0) | 0.007 |
| International normalized ratio | 1.0 (0.9–1.1) | 0.9 (0.8–1.0) | 1.0 (0.9–1.1) | <0.001 |
| Blood biochemistry | ||||
| Total bilirubin (mmol/L) | 11.8 (9.3–15.8) | 11.1 (8.7–14.5) | 14.2 (10.5–20.4) | 0.001 |
| Alanine aminotransferase (U/L) | 31.0 (18.5–52.5) | 29.0 (17.0–52.0) | 33.0 (22.5–55.2) | 0.178 |
| Aspartate aminotransferase (U/L) | 36.0 (25.9–55.0) | 31.0 (23.0–49.0) | 50.0 (33.7–67.0) | <0.001 |
| Albumin (g/L) | 31.6 (28.3–35.5) | 32.5 (29.7–36.2) | 28.9 (25.6–32.3) | <0.001 |
| Creatinine (μmol/L) | 70.8 (60.0–87.4) | 69.0 (56.9–82.0) | 76.7 (65.2–101.9) | 0.003 |
| Blood urea nitrogen (mmol/L) | 5.1 (3.7–7.0) | 4.6 (3.3–5.9) | 7.0 (5.2–10.5) | <0.001 |
| Lactate dehydrogenase (U/L) | 320 (229–448) | 276 (216–377) | 457 (372–669) | <0.001 |
| Creatine kinase (U/L) | 91 (57–147) | 89 (55–135) | 109 (58–239) | 0.149 |
| Creatine kinase-MB (U/L) | 14 (9–19) | 11.8 (9.0–17.0) | 18.0 (15.0–25.0) | <0.001 |
| Myoglobin (ng/ml) | 61.8 (37.9–125) | 50.1 (31.4–90.0) | 114.2 (59.2–179) | <0.001 |
| Troponin I (pg/ml) | 7.0 (2.0–18.4) | 4.0 (1.2–9.4) | 20.7 (9.6–115.4) | <0.001 |
| Infection-related biomarkers | ||||
| C-reactive protein (mg/L) | 42.2 (10.6–122) | 24.2 (6.0–66.5) | 126 (57.7–160) | <0.001 |
| Interleukin-6 (pg/mL) | 9.5 (6.5–13.4) | 8.9 (6.3–13.4) | 10.7 (7.9–13.6) | 0.063 |
| B-type natriuretic peptide (pg/ml) | 61.9 (26.0–170) | 34.8 (17.0–74.6) | 109 (50–299) | 0.001 |
| Blood gas analysis | ||||
| PaO2 (mm Hg) | 10.3 (8.4–16.4) | 11.1 (9.1–19.7) | 9.0 (6.8–13.5) | 0.014 |
| PaCO2 (mm Hg) | 5.1 (4.3–6.8) | 5.1 (4.5–5.8) | 4.7 (3.8–8.2) | 0.447 |
| SaO2 (%) | 96 (91–98) | 96 (95–99) | 91 (88–96) | 0.001 |
Nonparametric continuous variables were expressed as median (interquartile range [IQR]) and compared using Student's t-test or Mann-Whitney U test. P value <0.05 was considered statistically significant.
Abbreviations: APTT activated partial thromboplastin time; PaO2 partial pressure of oxygen in artery; PaCO2 partial pressure of carbon dioxide in artery; SaO2 oxygen saturation.