Figure 2.

SARS-CoV-2-Neutralizing Antibodies Can Bind to Murine Tissue

Immunofluorescence staining of SARS-CoV-2 mAbs (green) on murine organ sections showed specific binding to distinct anatomical structures.

(A) Staining of hippocampal neuropil with CV07-200 (cell nuclei depicted in blue).

(B) Staining of bronchial walls with CV07-222.

(C) Staining of vascular walls with CV07-255.

(D) Staining of intestinal walls with CV07-270.

Smooth muscle tissue in (B)–(D) was co-stained with a commercial smooth muscle actin antibody (red). Scale bars, 100 μm. See also Table S3.