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. 2020 Oct;26(10):2515–2517. doi: 10.3201/eid2610.200232

Table. PEP recipients and factors associated with inappropriate administration of PEP, suburban Cook County, IL, 2015–2018*.

Variable Total, no. (%), n = 611 Exposure met ACIP guidelines for PEP administration, no. (%)
Unadjusted GEE model†
OR (95% CI) Adjusted GEE model‡
aOR (95% CI)
Yes, n = 272 No, n = 339
District§
North 309 (50.6) 125 (45.9) 184 (54.3) Referent Referent
West 131 (21.4) 54 (19.9) 77 (22.7) 0.97 (0.52–1.80) 0.76 (0.39–1.47)
Southwest 82 (13.4) 47 (17.3) 35 (10.3) 0.51 (0.27–0.94) 0.41 (0.20–0.83)
South
89 (14.6)
46 (16.9)
43 (12.7)
0.64 (0.35–1.15)
0.52 (0.27–0.98)
Age, y
0–5 47 (7.7) 24 (8.8) 23 (6.8) 0.84 (0.44–1.62) 0.74 (0.36–1.50)
6–17 170 (27.8) 64 (23.5) 106 (31.3) 1.46 (0.92–2.32) 1.49 (0.90–2.45)
18–25 50 (8.2) 23 (8.5) 27 (8.0) 1.03 (0.55–1.94) 1.20 (0.53–2.72)
>26
344 (56.3)
161 (59.2)
183 (54.0)
Referent
Referent
Sex
F 317 (51.9) 131 (48.2) 186 (54.9) Referent Referent
M
294 (48.1)
141 (51.8)
153 (45.1)
0.76 (0.53–1.10)
0.77 (0.51–1.15)
Exposing animal
Bat 393 (64.3) 181 (66.5) 212 (62.5) Referent Referent
Cat 35 (5.7) 6 (2.2) 29 (8.6) 4.13 (1.62–10.50) 4.15 (1.49–11.60)
Dog 111 (18.2) 39 (14.3) 72 (21.2) 1.58 (0.91–2.72) 2.05 (1.07–3.96)
Raccoon 31 (5.1) 26 (9.6) 5 (1.5) 0.16 (0.06–0.45) 0.19 (0.06–0.57)
Other
41 (6.7)
20 (7.4)
21 (6.2)
0.90 (0.45–1.79)
0.93 (0.43–2.01)
HD consult¶
Yes 183 (30.0) 138 (50.7) 45 (13.3) 0.15 (0.09–0.23) 0.13 (0.08–0.22)
No 428 (70.0) 134 (49.3) 294 (86.7) Referent Referent

*ACIP, Advisory Committee on Immunization Practices; aOR, adjusted odds ratio; GEE, generalized estimating equation; HD, health department; PEP, rabies postexposure prophylaxis; OR, odds ratio.
†Bivariate GEE model for PEP inappropriateness as a function of the given categorical variable.
‡Multivariable GEE model for PEP inappropriateness as a function of all the predictors included in the table.
§Suburban Cook County residential district of patient’s home address.
¶Whether healthcare provider contacted a state or local health department to discuss appropriateness of PEP.