Table. Test performance of pooled specimens compared with individual specimens for severe acute respiratory syndrome, virus 2.
No. specimens in pool | Amplification in E or RdRp gene, % | No amplifications | Sensitivity of pools, % (95% CI) | Cumulative sensitivity, %* |
---|---|---|---|---|
2 | 100 | 0 | 100 (96–100) | 100 |
4 | 100 | 0 | 100 (96–100) | 100 |
6 | 100 | 0 | 100 (96–100) | 100 |
8 | 97 | 3 | 97 (92–99) | 97 |
10 | 99 | 1 | 99 (95–100) | 96 |
16 | 96 | 4 | 96 (90–98) | 92 |
*Calculated sensitivity based on the accumulated discrepancy numbers under the dilution fold