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. 2020 Oct;26(10):2469–2472. doi: 10.3201/eid2610.201955

Table. Test performance of pooled specimens compared with individual specimens for severe acute respiratory syndrome, virus 2.

No. specimens in pool Amplification in E or RdRp gene, % No amplifications Sensitivity of pools, % (95% CI) Cumulative sensitivity, %*
2 100 0 100 (96–100) 100
4 100 0 100 (96–100) 100
6 100 0 100 (96–100) 100
8 97 3 97 (92–99) 97
10 99 1 99 (95–100) 96
16 96 4 96 (90–98) 92

*Calculated sensitivity based on the accumulated discrepancy numbers under the dilution fold