Table 4. List of p-values. To take into account interindividual variation, the sufficient-summary-statistic approach (SSS) described in [35] as well as a nested ANOVA (nANOVA) was used. In both approaches, random effects were assumed. In the second and third row, where the results of the Shapiro-Wilk test (SW) are reported for the CO and PD group, p-values larger than the 5% are printed in bold, indicating that the observed distribution is no rare statistical realization under the assumption of a normal distribution as the null hypothesis. In the fourth and fifth row, the SSS and nANOVA results are tabulated with the smallest p-values highlighted.

Element	SW (CO)	SW (PD)	SSS	nANOVA
Mn	4.04e-10	1.71e-10	1.00	0.64
Fe	1.14e-4	1.32e-10	0.82	0.42
Cu	6.20e-3	9.79e-1	0.07	0.07
Zn	5.79e-3	2.00e-1	0.51	0.57
As	9.94e-8	1.65e-3	0.96	0.45
Se	1.67e-1	3.09e-3	0.26	0.34
Br	3.53e-10	4.71e-6	0.36	0.52