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. 2020 Sep 23;15(9):e0239396. doi: 10.1371/journal.pone.0239396

Fig 1. TRI MP administration reduces incidence and severity of CIA onset.

Fig 1

A) Survival curve indicating percentage of mice that remained arthritis free (score of 0 for all paws). B) Arthritis scores over time. A two-way ANOVA was performed, followed by Tukey post-hoc analysis to compare the mean of every group with the mean of every other group at each time point. Significance labels apply to all time points from Day 32 on. C-D) Average number of paws per mouse with arthritis score greater than or equal to specified threshold of 1 (C) or 3 (D) at Day 40. n = 24 mice per group, data presented as mean ± SEM, and the following cutoffs were used for significance: * p < 0.05, ** p < 0.01, **** p < 0.0001.