Fig 5. TRI MP reduces conventional T cell expansion and expands regulatory population not only for the draining lymph node, but also for a non-arthritic immunization in the contralateral lymph node.

A) Number of live cells in draining iLN as determined using counting beads. B) Percentage of CD4⁺ T cells expressing the proliferation marker Ki67 in the the draining LN. C) Percentage of CD4⁺ T cells that are FoxP3^-CD25⁺ in the draining LN. D-F) Same as A-C, but for the contralateral LN instead of the draining LN. n = 6 mice per group, data presented as mean ± SEM, and the following cutoffs were used for significance: ** p < 0.01, *** p < 0.001.