Extended Data Fig. 3. Urod depletion induces an immune suppressive and pro-tumorigenic transcriptional program in LLC cells.
a-b, Gene Set Enrichment Analysis highlighting expression of top gene sets significantly increased in LLC cells expressing Urod shRNA. c, Ingenuity Pathway Analysis demonstrating a decrease in expression of genes involved in immune cell recruitment and migration. Graph represents biological processes plotted against their bias adjusted z-scores. Transcriptional analysis was performed on n=3 biological (cell culture) replicates per group.