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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Nat Cancer. 2020 Apr 20;1(5):533–545. doi: 10.1038/s43018-020-0056-0

Extended Data Fig. 3. Urod depletion induces an immune suppressive and pro-tumorigenic transcriptional program in LLC cells.

Extended Data Fig. 3.

a-b, Gene Set Enrichment Analysis highlighting expression of top gene sets significantly increased in LLC cells expressing Urod shRNA. c, Ingenuity Pathway Analysis demonstrating a decrease in expression of genes involved in immune cell recruitment and migration. Graph represents biological processes plotted against their bias adjusted z-scores. Transcriptional analysis was performed on n=3 biological (cell culture) replicates per group.