Table 5.
TAVR procedure related complications according to first and next generation TAVR prosthesis.
| Complication /Related procedure | First generation TAVR | NStudies/NPatients | Next generation TAVR | NStudies/NPatients | p value |
|---|---|---|---|---|---|
| PM Implantation (%) | 17.12 ± 11.64 | 177/51,104 | 16.99 ± 9.66 | 58/11,024 | 0.681 |
| PVL II–III | 12.39 ± 9.38 | 74/17,877 | 1.75 ± 2.43 | 48/7,942 | < 0.000 |
| TIA (%) | 0.87 ± 1.24 | 35/18,061 | 1.95 ± 3.29 | 7/1,484 | 0.972 |
| Stroke (%) | 2.73 ± 2.49 | 160/46,931 | 2.09 ± 2.93 | 52/9,893 | 0.009 |
| Myocardial infarction (%) | 1.39 ± 2.22 | 118/42,851 | 0.45 ± 0.97 | 42/8,127 | < 0.000 |
| Coronary obstruction (%) | 0.99 ± 1.47 | 25/7,314 | 0.13 ± 0.29 | 22/3,350 | 0.004 |
| Vascular complication (%) | 11.51 ± 7.23 | 122/33,242 | 5.42 ± 4.75 | 51/7,904 | < 0.000 |
| Cardiac Reintervention (%) | 1.86 ± 1.28 | 11/2,705 | 0.38 ± 0.866 | 18/3,252 | 0.002 |
| Surgical replacement (%) | 2.54 ± 3.19 | 59/20,096 | 0.54 ± 1.55 | 30/4,983 | < 0.000 |
| Balloon (%) | 16.73 ± 15.15 | 40/11,982 | 12.83 ± 14.12 | 14/1,109 | 0.252 |
| Bleeding (%) | 9.27 ± 6.12 | 96/36,200 | 7.48 ± 6.62 | 45/9,014 | 0.049 |
| Death (%) | 5.41 ± 4.35 | 186/55,322 | 1.47 ± 1.73 | 54/10,088 | < 0.000 |
Significant p values are indicated in bold.
PM pacemaker, PVL paravalvular leakage, TIA transitory ischemic attack.