Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 23;10:15483. doi: 10.1038/s41598-020-72459-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Evolutionary facets of the genetic clones in the skin microenvironment. Combined data from SVs and CNA for each sample was subjected to phylogenetic analysis to identify genetic subclones. (A) Rainbow graph representing the number and proportion of the subclones identified in each sample. (B) Bubble plot representing the correlation between the TCRβ clonotypes and the genetic subclones. The number of TCRβ clonotypes are represented as Log2 scale. (C) Phylogenetic trees are composed of stem and clades (also recognized as branches). Bar graph represents the percentage of all mutations in each section (stem and clade) of the phylogenetic tree. The blue and red colour represents the mutations in stem and clades respectively (D) Mutational landscape of the putative driver genes in the different sections of the phylogenetic tree for two layers of skin (epidermis and dermis). Function significance of the mutations include missense, frameshift, insertions, deletions, stop gain or loss and variant in 3′ and 5′ UTR. No colour indicates absence of mutation in the sample.