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. 2020 Sep 23;6:93. doi: 10.1038/s41420-020-00324-9

Fig. 6. Comparison of the biological actions of activin-A on the expression of steroidogenic enzyme StAR on luteal granulosa cells cultured with fetal bovine serum (FBS) vs. follicular fluid (FF).

Fig. 6

Note the substantial decrease in the staining intensity of StAR and reduced P4 output after activin-A treatment similar to what it is observed in the cells cultured with FBS. hCG was associated significant increase in the StAR expression and P4 production, confirming its well-known luteotropic effects in both types of culture condition.