Table 5.

Estimated mean change (± standard error) in weight and cardiovascular risk factors from baseline to Weeks 26 and 52, and from Weeks 26 to 52

Variable	BWL+BIAS	BWL	Mean Difference	p	d
Percent Weight Change
Week 26	−4.5±1.0***	−5.9±1.0***	1.4±1.4	0.31	0.26
Week 52	−3.1±1.0**	−4.0±1.0***	0.9±1.5	0.53	0.14
Week 26 to Week 52	1.4±0.6*	1.9±0.6**	−0.5±0.9	0.59	0.09
Waist Circumference (cm)
Week 26	−4.3±0.9***	−5.1±0.9***	0.8±1.3	0.54	0.15
Week 52	−4.4±1.0***	−4.4±1.0***	0.0±1.5	0.99	0.00
Week 26 to Week 52	−0.1±0.9	0.7±0.9	−0.8±1.2	0.54	0.16
Systolic Blood Pressure (mm Hg)+
Week 26	−2.6±1.6	−2.4±1.6	−0.2±2.2	0.94	0.01
Week 52	−5.7±2.5*	−4.3±2.5	−1.4±3.6	0.71	0.09
Week 26 to Week 52	−3.1±2.5	−1.9±2.5	−1.2±3.5	0.73	0.09
Diastolic Blood Pressure (mm Hg)+
Week 26	−1.4±1.2	−2.1±1.1	0.7±1.6	0.67	0.08
Week 52	−1.1±1.3	−1.8±1.3	0.7±1.9	0.72	0.08
Week 26 to Week 52	0.4±1.3	0.3±1.3	0.0±1.9	0.98	0.01

Note. Week 26 values from the original report are presented. Percent weight change was calculated from week 1 weights; all other values were measured at screening.

⁺Blood pressure analyses control for whether or not participant took blood pressure medication at any time during the study. Asterisks indicate significance of within group changes from baseline to time point.

^***p≤0.001

^**p<0.01

^*p<0.05