Table 4.

Moderate/High impact coding variants that fall within adiposity QTL and are supported by SDP and/or literature search

Trait	QTL	Candidate Gene	SNP In LD With Peak Marker	SNP. change	Amino. acid. change	effect	impact	ACI	BN	BUF	F344	M520	MR	WN	WKY	Literature Support
Fasting Glucose	chr10:109 Mb	Rnf213	chr10:108582280	c.9502C>G	p.His3168Asp	missense_variant	MODERATE	GG	CC	GG	GG	GG	GG	GG	GG	PMID 2341075
			chr10:108582544	c.9766T>C	p.Trp3256Arg	missense_variant	MODERATE	CC	TT	CC	CC	CC	CC	CC	CC
			chr10:108604073	c.12263G>C	p.Ser4088Thr	missense_variant	MODERATE	CC	GG	CC	CC	CC	CC	CC	CC
Fasting Glucose	chr14:86 Mb	Xbp1	chr14:85756355	c.397A>G	p.Asn133Asp	missense_variant	MODERATE	AA	AA	AA	AA	AA	AA	AA	GG	366 Pubmed articles for Xbp1, glucose
BMI_Tail	chr1:282 Mb	Prlhr	chr1:281755911	c.3G>A	p.Met1?	start_lost	HIGH	CC	CC	TT	CC	CC	CC	CC	TT	PMID 29193816
Body Weight			chr1:281755911	c.3G>A	p.Met1?	start_lost	HIGH	CC	CC	TT	CC	CC	CC	CC	TT
ParaFat			chr1:281755911	c.3G>A	p.Met1?	start_lost	HIGH	CC	CC	TT	CC	CC	CC	CC	TT
RetroFat			chr1:281755911	c.3G>A	p.Met1?	start_lost	HIGH	CC	CC	TT	CC	CC	CC	CC	TT
EpiFat			chr1:281755911	c.3G>A	p.Met1?	start_lost	HIGH	CC	CC	TT	CC	CC	CC	CC	TT
RetroFat	chr6:28 Mb	Adcy3	chr6:28572363	c.362T>C	p.Leu121Pro	missense_variant	MODERATE	TT	TT	TT	TT	TT	TT	TT	CC	PMID 29193816
Body Length_Tail	chr8:118 Mb	Ngp	chr8:118664419	c.316C>T	p.Gln106*	stop_gained	HIGH	TT	CC	CC	CC	CC	CC	CC	CC	none