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. 2020 Sep 10;11:2138. doi: 10.3389/fimmu.2020.02138

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Copyright © 2020 Yan, Jiang, Gu, Feng, Zhang, Lv and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic pathway analysis of SLE-altered metabolites using MetaboAnalyst 4.0 based on the KEGG. Circle colors indicate pathway enrichment significance. Circle size indicates the extent of pathway impact. Circle above the red line (–Log₁₀ P > 1.30) represents significantly enriched pathway. (A) Pathway enrichment analysis based on KEGG full library. (B) Pathway enrichment analysis based on KEGG Homo sapiens library. SLE, systemic lupus erythematosus; KEGG, Kyoto Encyclopedia of Genes and Genomes.