Table 1.
Investigations | Results | Reference |
---|---|---|
Fibrinogen (g/L) | 7.7 | 1.8–4.5 |
d-dimer (ug/mL) | 2.55 | < 0.5 |
APTT (s) | 38.9 | 27–37 |
PT (s) | 14.3 | 11–14 |
Factor II (%) | 133 | 70–120 |
Factor V (%) | 134 | 70–120 |
Factor VIII (%) | 498 | 70–120 |
Factor IX (%) | 202 | 70–120 |
Von Willebrand factor antigen (%) | 371 | 56–160 |
C-reactive protein (mg/L) | 200 | 0–5 |
ESR mm/h | 70 | |
Lupus anticoagulant | Weakly positive | |
Anti-cardiolipin IgG (GPL units) | 35 | 0–20 |
Anti-cardiolipin IgM (MPL units) | 28 | 0–20 |
Anti-Sm, anti-RNP, anti-Jo 1, anti-SCL 70, anti-Ro, anti-La (RU/mL) | < 20 | 0–20 |
Paraneoplastic antibody panel (anti-Hu, anti-Yo, Anti-Ri, anti-CV2, anti-amphiphysin, anti-PNMA2/Ta, anti-recoverin, anti-SOX1, anti-titin, anti-Zic4, anti-GAD65, anti-Tr) | Negative | |
24-h urinary noradrenaline (nmol/d) | 642 | 89–473 |
24-h urinary normetanephrine (nmol/d) | 5559 | 885–2880 |
ACTH (pmol/L) | 4 | |
8 am cortisol (nmol/L) | 310 | 240–618 |
Short Synacthen test (nmol/L) | ||
0 min | 194 | |
30 min | 537 | |
60 min | 590 | |
Autonomic function test | ||
Blood pressure (mmHg) | Heart rate (/min) | |
Supine | 117/78 | 70 |
Standing (3 min) | 125/89 | 105 |
Supine | 118/78 | 67 |
60-degree tilt (5 min) | 134/85 | 98 |
Respiratory sinus arrhythmia | 25/min | |
Blood pressure before and after isometric exercise | 115/77; 128/87 | |
Blood pressure before and after cold pressor stimulus | 115/76; 126/83 | |
Lying to standing 30:15 ratio 1.31 | ||
Sympathetic skin response was present in palm and sole | ||
The Valsalva maneuver could not be done because of COVID-19 infection control restrictions |
APTT activated partial thromboplastin time, PT prothrombin time, ESR erythrocyte sedimentation rate