Table 3.

Data items to be collected from the selected studies

Features of the study	Patients’ characteristics	Intervention	Outcome
Title, author	Age, gender	Time from onset to imaging	Permeability values
Study design	Comorbidities	Imaging characteristics	Final lesion (volume)
Recruitment procedure and duration	NIHSS at admission	BBBP assessment characteristics	Follow-up (length, number)
Number of participants	Stroke aetiology (TOAST classification)	Reperfusion treatment given	Clinical outcome (NIHSS and mRS)
Imaging modality	Vascular territory		Haemorrhagic transformation

BBBP, blood-brain barrier permeability; mRS, Modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; TOAST, Trial of ORG 10172 in Acute Stroke Treatment.