FIGURE 4.

Shikimic acid production titer in SA-7 strains harboring each shikimate pathway gene expression plasmid. Blue bars indicate SA production when the CGXII medium containing 50 g/L of glucose was used as the sole carbon source. Orange bars indicate the CGXIIY medium used. The data are presented as the average of three independent experiments, and error bars indicate the standard deviation. P values were computed using the two-tailed Student’s t-test (*P < 0.05; **P < 0.01).