Table 1.
Characteristics of UK Biobank dataset of 13,680 participants (*12,730 participants for the cognition variable reaction time and education due to missingness). SD: standard deviation; WHR: waist-to-hip ratio; APOE: apolypoprotein-E; CVR: cerebrovascular risk; WMH: white matter hyperintensity.
| Characteristics | Levels (N) | Mean (SD) | Median (range) |
|---|---|---|---|
| Age (years) | – | 62.9 (7.4) | 63.5 (45.1; 80.7) |
| Sex | Men (6,444), Women (7,236) | – | – |
| Head size | – | 1.3 (0.1) | 1.3 (0.9; 1.8) |
| Hypertension risk | 0 (7,272), 1 (6,408) | – | – |
| Hypercholesterolemia | 0 (10,899), 1 (2,781) | – | – |
| Diabetes | 0 (13,017), 1 (663) | – | – |
| Smoking (score/pack years) | 0 (11,291), 1 (2,238), 2 (151) | 4.9 (11.4) | 0 (0; 141) |
| WHR (indicator/continuous) | 0 (7,251), 1 (6,429) | 0.9 (0.1) | 0.9 (0.6; 1.2) |
| APOE- status | 0 (10,226), 1 (3,150), 2 (304) | – | – |
| CVR score | 0 (2,596), 1 (4,204), 2 (3,770), | 1.7 (1.2) | 2 (0; 7) |
| 3 (1,947), 4 (869), 5 (252), | |||
| 6 (36), 7 (6), 8 (0) | |||
| WMH load (2 mm3 voxels) | – | 528.6 (667.7) | 310.0 (3; 8,228) |
| Reaction time* (milliseconds) | – | 585.4 (104.9) | 569 (272; 1,559) |
| Years of education | 7 (780), 10 (1,679), 13 (757), 15 (1,481), 19 (2,027), 20 (6,006) | 16.7 (4.3) | 19 (7; 20) |