Table 1.

Involvement of natural antibodies in immune responses and immune status.

	References
Initiation of apoptosis	(6, 17)
Complement activation	(8–10, 18)
FcR-mediated phagocytosis	(10, 19)
Neutralization of infective agents	(6, 18, 20, 21)
Adjuvanting properties	(14, 22)
Maturation of dendritic cells	(15, 16)
Clearance of senescent/necrotic cells	(23, 24)
Prevention of autoimmunity	(17, 25–28)
Opsonization of antigens	(11)
Enhancement of antigenicity	(12)
Antigen targeting to lymph nodes	(13, 18)
T cell proliferation	(29)
Allograft rejection	(30)