Table 3.
Involvement of natural antibodies in prevention or combat of infection.
| Antigen(s) | Isotype | Infection | Effect | References |
|---|---|---|---|---|
| Self- and microbiota | IgM, IgA | Microbiota | Protection | (37) |
| Glycans and microbiota | Not specified | Microbiota | Orchestration | (43) |
| Carbohydrates | IgM | Microbiota | (44) | |
| LPS,KLH, Peptidoglycan |
IgM, IgG, IgA | Unknown | Heritable | (88) |
| PC-rich | IgM | S. pneumonia | Protection | (89, 148) |
| Streptococcus pneumonia | ||||
| OxLDL, T15 idiotype | ||||
| VSV virus, Listeria | IgM | VSV virus, Listeria | Protection | (90) |
| Influenza strains | Not specified | Influenza | Protection | (91) |
| Malaria | IgM, IgG | Malaria | Protection | (97) |
| Schistosome | Schistosomiasis | |||
| myelin basic protein | IgG | Porcine reproductive | Protection? | (119) |
| respiratory syndrome virus | ||||
| Phospholipids | IgM | Tuberculosis | Protection? | (156) |
| Virulence-associated | IgM, IgG | S. pneumonia | (157) | |
| Protein | ||||
| self-antigens, | IgM | Microbiota | Protective? | (18) |
| Phospholipids, | ||||
| T-cell independent- | ||||
| antigens | ||||
| CCR5 | Not specified | HIV | Protective? | (158) |
| Pantoea-1 microbes | IgG | E. coli | Protective | (159) |
| Aeromonas salmonicida | IgM | A. salmonicida | Protective | (160) |
| Chicken red blood cells | not specified | Classical swine fever | Protective? | (161) |
| KLH | IgM | E. coli | Protective | (162) |
| Phosphatidylcholine | IgG | Plasmodium chabaudi | Protective | (165) |
| Galα1-3Galβ1-GlcNAc | IgM, IgG, IgA | Block infections | (43, 44, 54, 155) |