Table 4.

Results of gPPI analysis for the effects of EMPATHIC WATCH and REAPPRAISAL, with the time series of a seed in the IFG. Regions were classified using the Harvard–Oxford Atlas, z > 3.1 and (corrected) cluster significance P < 0.05. Z-MAX values represent peak activity for the cluster. MNI coordinates

Volume	Z-MAX	X	Y	Z	R/L
Functional connectivity of the IFG during EMPATHIC WATCH condition
Painful scenario > non-painful scenario
215	3.041	20	−50	14	R	Precuneus, supracalcarine cortex
110	3.1602	−28	−50	16	L	Precuneus, supracalcarine cortex
105	2.7229	−38	−38	58	L	Post-central gyrus
57	2.9896	−32	−24	40	L	Post-central gyrus
44	2.8075	−16	20	34	L	Middle cingulate gyrus
38	2.8298	2	−18	48	R	Mid-cingulate, supplementary motor area
37	2.6564	−64	4	−4	L	Superior temporal gyrus
35	2.7188	−50	−20	28	L	Supramarginal gyrus
33	2.473	4	−2	36	R	Anterior cingulate gyrus
31	2.7528	−4	−28	−4	L	Thalamus
27	2.6531	22	−46	34	R	Precuneus
22	2.8328	−54	−4	−28	L	Middle temporal gyrus
21	2.7157	54	−40	54	R	Supramarginal gyrus
Non-painful scenario > painful scenario
110	−2.9173	56	−34	−6	R	Middle temporal gyrus
67	−2.9378	−2	−42	−8	L	Cerebellum left I–IV
35	−2.7737	−44	22	12	L	Inferior frontal gyrus
34	−2.8068	−10	48	42	L	Superior frontal gyrus
Volume	Max Int	X	Y	Z	R/L
Functional connectivity of the IFG during REAPPRAISAL condition
Painful scenario > non-painful scenario
166	3.0999	−48	−74	20	L	Lateral occipital cortex
80	3.1135	32	−88	24	R	Lateral occipital cortex
48	2.6958	−60	8	6	L	Inferior frontal gyrus
41	2.5736	−40	−38	18	L	Insula
40	2.8461	−32	−8	−30	L	Parahippocampal gyrus, temporal fusiform cortex
30	2.591	−58	−34	−6	L	Middle temporal gyrus
26	2.5268	−60	−16	8	L	Planum temporale
24	2.8386	−22	−64	70	L	Lateral occipital cortex
21	2.5674	−52	−8	−28	L	Inferior temporal gyrus
166	3.0999	−48	−74	20	L	Lateral occipital cortex
80	3.1135	32	−88	24	R	Lateral occipital cortex
Non-painful scenario > painful scenario
24	−2.7775	70	−40	20	R	Supramarginal gyrus