Table 2.

Comparison of epithelial-mesenchymal transition biomarkers immunoexpression between metastatic and non-metastatic oral squamous cell carcinoma groups using MATLAB software

Biomarker	Group	n	Minimum	Maximum	Mean±SD	P
Proportion of E-cadherin-positive cells	Metastatic	20	10	20	13.95±2.395	0.000
	Non-metastatic	20	14	58	29.20±11.678
Intensity of E-cadherin-positive cells	Metastatic	20	140	166	151.60±7.970	0.000
	No-nmetastatic	20	138	180	163.80±10.871
Proportion of membranous β-catenin-positive cells	Metastatic	20	10	20	13.95±2.395	0.000
	Non-metastatic	20	14	58	29.20±11.678
Proportion of cytoplasmic β-catenin-positive cells	Metastatic	20	3	13	6.80±2.587	0.343
	Non-metastatic	20	2	12	6.05±2.350
Intensity of membranous and cytoplasmic β-catenin-positive cells	Metastatic	20	140	166	151.60±7.970	0.000
	Non-metastatic	20	138	180	163.80±10.871
Proportion of MMP-2-positive tumor cells	Metastatic	20	20	34	29.10±3.553	0.000
	Non-metastatic	20	17	25	18.85±1.981
Intensity of MMP-2-positive tumor cells	Metastatic	20	154	189	180.20±9.855	0.00
	Non-metastatic	20	163	170	165.70±1.689
Proportion of MMP-2-positive stromal cells	Metastatic	20	26	43	34.80±4.819	0.000
	Non-metastatic	20	19	30	24.15±3.083
Intensity of MMP-2-positive stromal cells	Metastatic	20	162	190	183.35±7.782	0.376
	Non-metastatic	20	162	198	185.55±7.756
Proportion of MMP-9-positive tumor cells	Metastatic	20	25	29	27.35±1.226	0.000
	Non-metastatic	20	11	16	13.75±1.650
Intensity of MMP-9-positive tumor cells	Metastatic	20	163	184	176.15±3.843	0.000
	Non--metastatic	20	158	179	167.85±5.509
Proportion of MMP-9-positive stromal cells	Metastatic	20	26	33	29.50±1.792	0.000
	Non-metastatic	20	10	26	18.95±5.063
Intensity of MMP-9-positive stromal cells	Metastatic	20	175	189	186.05±2.982	0.000
	Non-metastatic	20	156	180	164.50±5.155

MMP: Matrix metalloproteinase, SD: Standard deviation