Fig. 3.

Risk of all-cause mortality for use of antipsychotics compared with non-use of antipsychotics after clozapine discontinuation, between-individual model.

In bold are depicted the agents that are significant after Bonferroni correction (P < 0.003125). Hazard ratios are adjusted for gender, age at clozapine discontinuation, number of previous ward admissions owing to psychosis and time since first schizophrenia diagnosis, concomitant use of other medication and comorbidities. Antipsychotic polypharmacy refers to the use of two or more antipsychotics concomitantly.