Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 23;10:15530. doi: 10.1038/s41598-020-72661-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Epigenomic screening, validation and re-validation of response marker for HER2-positive breast cancers. (A) Workflow of the screening by DNA methylation analysis of the screening set, including 14 samples with pCR and 20 samples with non-pCR. Details are explained in the text. (B) Methylation levels of 6 genes measured by pyrosequencing in the validation set. Differential methylation of only HSD17B4 was validated (P = 0.003). (C) Methylation levels of HSD17B4 in the re-validation set. Differential methylation of HSD17B4 was re-validated (P = 0.0007).