Table 1.

Overall patient characteristics and biopsy outcomes at vs outside NCI

	Mean Before Matching				Mean After Matching
	NCI	Outside	Difference	p Value	NCI	Outside	Difference	p Value
No. pts	620	310	–	–	510	310	–	–
Age	62.1	65.4	3.2	<0.0001	65.6	65.4	−0.2	0.7328
PSA (ng/ml)	11.9	10	−1.9	0.5437	10.4	10	−0.5	0.5521
% Suspicion:				<0.0001				0.9543
Low	11	6.5	−4.5		6.2	6.5	0.3
Moderate	70.6	88.7	18.1		89.4	88.7	−0.7
High	18.4	4.8	−13.5		4.4	4.8	0.4
% Prior neg biopsy	68.5	60	−8.5	0.0119	64.6	60	−4.6	0.2343
% CDR:
By FB	40	53.2	13.2	0.0002	39.1	53.2	14.2	0.0054
By SB + FB	47.3	64.5	17.3	<0.0001	47.2	64.5	17.3	0.0004
% Upgrading:
By FB	38.2	33	−5.2	0.2754	26.1	33	6.9	0.2701
By random biopsy	22.2	29.5	7.3	0.0832	32.3	29.5	−2.8	0.6829
Clinically significant* by FB	21.2	20.5	−0.7	0.9487	17.5	20.5	3	0.5987
Clinically significant* by SB	6.8	9.5	2.7	0.3627	14.7	9.5	−5.2	0.244

^*Defined as Gleason 3 + 4 = 7 or greater.