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Four examples of PIK3CA mutant GISTs. (a) An epithelioid GIST of the stomach. (b) A retroperitoneal spindle cell GIST with Verocay body-like, prominent aggregates of cell processes, typically seen in GISTs of intestinal origin. (c) A GIST with spindled to ovoid cell morphology. (d) A spindle cell GIST representing the morphology often seen in intestinal GISTs.
