Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Asymmetric Dihydroxylation of Olefin 24
 | |
|---|---|
| Ligands screeneda | Compound 25, C25 ratio, epi:natural (R:S) |
| None | 2.2:1 |
| (DHQD)2PHAL | 1:1 |
| (DHQ)2PHAL | 9.5:1 (82%) |
| (DHQD)2PYR | 1:3.8 |
| (DHQ)2PYR | 2:1 |
| DHQD | 1.8:1 |
| DHQ | 2.5:1 |
Conditions: K2OsO4 (2 mol %), ligand (10 mol %), t-BuOH/H2O (1:1), 0 °C, 40 h.
