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Schematic diagram for the constructions of full-length Aβ1–42 peptides. The U-shaped Aβ monomers, Aβ17–42 and Aβ9–42, recover the missing N-terminal portions through the covalent connection with the solution structure of Aβ1–16 (pdb code: 1ZE7), generating two Aβ1–42 conformers (conformer 1 and 2) with different turns (from Jang et al. [8], reprinted with permission)
