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Conformations of pyroglutamate-modified Aβ (AβpE) peptide. Monomer conformations of AβpE3–42 with two different conformers, (a) conformer 1 with turn at Ser26-Ile31 and (b) conformer 2 with turn at Asp23-Gly29. (c) Molecular topology of the pyroglutamate at residue 3 (pE3). From Gilman et al. [42], reprinted with permission
