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. Author manuscript; available in PMC: 2020 Sep 24.
Published in final edited form as: Oncogene. 2015 Sep 14;35(20):2584–2591. doi: 10.1038/onc.2015.324

Figure 2.

Figure 2.

Characterization of HLA-I genes in BGC823 and AGS cells based on whole-genome sequencing data. (a) CNV of BGC823 (left) and AGS cells (right). From the outer to the inner ring: coordinate of chromosome, CNVs and regional depth. (b) Upper, CNV of BGC823 and AGS cells. Gains are indicated by red and losses in blue (see also Supplementary Table S2); middle, CNV of chromosome 6; lower, CNV of HLA-I in BGC823 and AGS cells. (c) qPCR assays of HLA-I in BGC823 and AGS cells. Data are means±s.d. (d) Western blot analysis of HLA-I in BGC823 and AGS cells. (e) NK cell cytotoxicity assays of BGC823 and AGS cells treated with IL-12 and a mixture of specific antibodies against HLA-I or IgG.