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. Author manuscript; available in PMC: 2020 Sep 24.
Published in final edited form as: Oncogene. 2015 Sep 14;35(20):2584–2591. doi: 10.1038/onc.2015.324

Figure 4.

Figure 4.

Expression patterns of HLA-I and the NKp30/VAV2/MAPK3/IL-12 pathway in GC cell lines. (a) qPCR detected relative CNV of HLA-A, B and C in GC cell lines. The value of HLA-I is the sum value of HLA-A, -B and -C. Owing to the copy number of HLA-A, -B was not changed in AGS cells, the relative copy number of HLA-A, -B was compared with AGS cells; for HLA-C, as it was lost in AGS cells, the relative copy number of HLA-C was compared with BGC823 cells. (b) Western blot analysis of NK cell cytotoxicity-related proteins in GC cell lines with high and low tumorigenic capacities.