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Autoinflammatory syndromes. Illustration of commonly targeted pathways. ASC, Apoptosis-associated speck-like protein; DAMP, danger-associated molecular pattern; IL, interleukin; NFκB, nuclear factor kappa B; NLRP, nucleotide-binding domain leucine-rich repeat-containing protein; PAMP, pathogen-associated molecular pattern; TLR, Toll-like receptor, TNF-α, tumor necrosis factor alpha.
