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. 2020 Sep 23;10:15479. doi: 10.1038/s41598-020-72484-8

Table 3.

Influence of three autoinducer (AI-1, AI-2 and AI-3) QS systems on the expression of virulence factors in A. hydrophila.

Autoinducer system Virulence factors Effect Strains Mutants References
AI-1 Exoprotease + A. hydrophila AH-1N ΔahyI and ΔahyR 18
β-Haemolysin
Biofilm + ΔahyI and ΔahyR 92
Proteases, amylase, Dnase, haemolysin and S-layer + A. hydrophila J-1 ΔahyR 93
T6SS(Hcp, VgrG), metallo-protease, biofilm + A. hydrophila{A. dhakensis} SSU ΔahyRI and ΔahyR+ 17,94
T3SS + A. hydrophila{A. piscicola} AH-3 ΔahyI and ΔahyR 69
Haemolysin A. hydrophila ATCC 7966 ΔahyI, ahyI-K7Q and ahyI-K7R 95
Protease +
Biofilm, proteases, haemolysin, amylase and Dnase + A. hydrophila YJ-1 ΔahyI 96
AI-2 Swimming motility + A. hydrophila {A.dhakensis} SSU ΔluxS 19
Biofilm
Biofilm, extracellular protease + A. hydrophila ATCC 7,966 ΔluxS 97
AI-3 Motility, cytotoxic enterotoxin, haemolysin, protease + A. hydrophila {A. dhakensis} SSU ΔqseB 20,94
Biofilm
Biofilm, haemolysin + A. hydrophila NJ-35 ΔqseC 98

“+” represents upregulation, and “−” represents downregulation.