Table 2.
Comparison of perinatal characteristics and the outcome of pregnancy between SCD women and non-SCD women seen in 4 maternity hospitals in Brazzaville between July 2017 and June 2019.
| Outcomes | SCD | Non-SCD | p | OR | 95% CI |
|---|---|---|---|---|---|
| Bacterial infections | |||||
| No | 46 (70.7%) | 124 (95.4%) | |||
| Yes | 19 (29.3%) | 6 (4.6%) | 0,001 | 21.7 | 7.6–62.7 |
| Mean gestation age (weeks) | 35 | 38 | |||
| Min–max | 28–42 | 29–42 | 0,0001 | ||
| Preterm birth | |||||
| No | 16 (24.6%) | 90 (69.2%) | |||
| Yes | 49 (75.4%) | 40 (30.8%) | 0,001 | 8.0 | 3.0–23.2 |
| Mode of delivery | |||||
| Vaginal | 24 (37%) | 86 (65.6%) | |||
| Cesarean | 41 (63%) | 46 (35.4%) | 0,001 | 3.1 | 1.6–5.7 |
| Mean birth weight (g) | 2400 | 3000 | |||
| Min–max | 1400–3750 | 2675–4100 | 0,001 | ||
| Low birth weight | |||||
| No | 31 (47.7%) | 109 (83.9%) | |||
| Yes | 34 (52.3%) | 21 (16.1%) | 0,001 | 4.7 | 2.4–9.4 |
| NICU (n = 188) | |||||
| No | 37 (59.7%) | 104 (82.5%) | |||
| Yes | 25 (40.3%) | 22 (17.5%) | 0,01 | 3.2 | 1.6–6.3 |
| Fetal/child death (n = 195) | |||||
| No | 51 (78.5%) | 120 (93.2%) | |||
| Yes | 14 (21.5%) | 10 (4.8%) | 0,01 | 4.3 | 1.5–12.2 |
| Maternal outcome | |||||
| Alive | 61 (93.8%) | 123 (94.6%) | |||
| Died | 4 (6.2%) | 7 (5.4%) | 0,9 | ||
NICU: neonatal intensive care unit; SCD: sickle cell disease; non-SCD: non-sickle cell disease; CI: confidence interval; OR: odds ratio.