Table 1. Characteristics of Persons With Active TB Disease and an Age-, Sex-, and Date of Diagnosis–Matched Cohort of Patients Without Active TB Disease Stratified by Survival Status in a Large, Integrated Health System, Kaiser Permanente Northern California, 1997-2017.
| Characteristic | Cohort, No. (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active TB | Comparison | ||||||||
| All | Living | Died | All | Living | Died | ||||
| In year 1 | After year 1 | In year 1 | After year 1 | ||||||
| Total | 2522 (100) | 1935 (76.7) | 176 (7.0) | 411 (16.3) | 100 880 (100) | 87 721 (87.0) | 1070 (1.1) | 12 089 (12.0) | |
| Sex | |||||||||
| Male | 1420 (56.3) | 1031 (53.3) | 114 (64.8) | 275 (66.9) | 56 088 (55.6) | 47 568 (54.2) | 706 (66.0) | 7814 (64.6) | |
| Female | 1102 (43.7) | 904 (46.7) | 62 (35.2) | 136 (33.1) | 44 792 (44.4) | 40 153 (45.8) | 364 (34.0) | 4275 (35.4) | |
| Age, y | |||||||||
| 0-24 | 231 (9.2) | 228 (11.8) | 2 (1.1) | 1 (0.2) | 9240 (9.2) | 9176 (10.5) | 5 (0.5) | 59 (0.5) | |
| 25-44 | 820 (32.5) | 789 (40.8) | 9 (5.1) | 22 (5.4) | 32 800 (32.5) | 32 249 (36.8) | 24 (2.2) | 527 (4.4) | |
| 45-64 | 849 (33.7) | 656 (33.9) | 46 (26.1) | 147 (35.8) | 33 960 (33.7) | 31 352 (35.7) | 154 (14.4) | 2454 (20.3) | |
| ≥65 | 622 (24.7) | 262 (13.5) | 119 (67.6) | 241 (58.6) | 24 880 (24.7) | 14 944 (17.0) | 887 (82.9) | 9049 (74.9) | |
| Race/ethnicitya | |||||||||
| Non-Hispanic | |||||||||
| White | 242 (9.6) | 126 (6.5) | 34 (19.3) | 82 (20.0) | 50 201 (49.8) | 41 176 (46.9) | 759 (70.9) | 8266 (68.4) | |
| Black | 181 (7.2) | 131 (6.8) | 23 (13.1) | 27 (6.6) | 6849 (6.8) | 5840 (6.7) | 85 (7.9) | 924 (7.6) | |
| Hispanic | 367 (14.6) | 290 (15.0) | 26 (14.8) | 51 (12.4) | 15 110 (15.0) | 13 871 (15.8) | 81 (7.6) | 1158 (9.6) | |
| Asian/Pacific Islander | 1448 (57.4) | 1156 (59.7) | 88 (50.0) | 204 (49.6) | 14 293 (14.2) | 13 227 (15.1) | 93 (8.7) | 973 (8.0) | |
| American Indian/Alaska Native/other/mixed race | 284 (11.3) | 232 (12.0) | 5 (2.8) | 47 (11.4) | 14 427 (14.3) | 13 607 (15.5) | 52 (4.9) | 768 (6.4) | |
| Comorbiditiesa | |||||||||
| Diabetes | 643 (25.5) | 402 (20.8) | 56 (31.8) | 185 (45.0) | 9476 (9.4) | 6623 (7.6) | 293 (27.4) | 2560 (21.2) | |
| End-stage kidney disease | 63 (2.5) | 16 (0.8) | 19 (10.8) | 28 (6.8) | 257 (0.3) | 112 (0.1) | 34 (3.2) | 111 (0.9) | |
| HIV infection | 64 (2.5) | 46 (2.4) | 9 (5.1) | 9 (2.2) | 260 (0.3) | 216 (0.2) | 3 (0.3) | 41 (0.3) | |
| Prior solid organ transplant | 19 (0.8) | 10 (0.5) | 4 (2.3) | 5 (1.2) | 84 (0.1) | 51 (0.1) | 5 (0.5) | 28 (0.2) | |
| History of cancer diagnosis | 183 (7.3) | 64 (3.3) | 57 (32.4) | 62 (15.1) | 4593 (4.6) | 2737 (3.1) | 297 (27.8) | 1559 (12.9) | |
| Active TB site at diagnosis | |||||||||
| Pulmonary and extrapulmonary | 173 (6.9) | 124 (6.4) | 19 (10.8) | 30 (7.3) | NA | NA | NA | NA | |
| Pulmonary only | 1216 (48.2) | 970 (50.1) | 80 (45.5) | 166 (40.4) | NA | NA | NA | NA | |
| Extrapulmonary only | 452 (17.9) | 381 (19.7) | 21 (11.9) | 50 (12.2) | NA | NA | NA | NA | |
| Data not available prior to July 2002 | 681 (27.0) | 460 (23.8) | 56 (31.8) | 165 (40.1) | NA | NA | NA | NA | |
Abbreviations: NA, not applicable; TB, tuberculosis.
a
Race/ethnicity and presence of selected comorbidities significantly different between active TB and comparison cohort for all categories (P < .001).