Table 1. Patient Characteristics Stratified by Mortality at Discharge.
Demographic Characteristics | Mean (SD) | P valuea | |
---|---|---|---|
Survivors | Nonsurvivors | ||
No. | 1365 | 276 | |
Age, y | 59.6 (17.6) | 74.6 (13.4) | <.001 |
Male, No. (%) | 723 (53) | 163 (59) | .07 |
BMI | 30.8 (6.8) | 30.2 (7.2) | .21 |
Race, No. (%) | |||
White/Caucasian | 585 (43) | 155 (56) | <.001 |
Black/African American | 223 (16) | 58 (21) | .04 |
All other/unknown | 41 | 23 | <.001 |
Ethnicity, No. (%) | |||
Hispanic | 448 (33) | 49 (18) | <.001 |
Non-Hispanic/unknown | 67 | 82 | <.001 |
RDW % stratified by age group | |||
<50 | 13.4 (1.9) | 15.8 (3.8) | <.001 |
50-59 y | 13.6 (2.1) | 14.8 (2.6) | .002 |
60-69 y | 13.8 (1.6) | 15.5 (2.2) | <.001 |
70-79 y | 14.1 (1.8) | 14.7 (2.0) | .03 |
≥80 | 14.2 (1.6) | 15.0 (1.8) | <.001 |
Entire cohort | 13.8 (1.8) | 15.0 (2.2) | <.001 |
Other laboratory tests | |||
Absolute lymphocyte count, N × 109/L | 1.24 (2.98) | 1.05 (1.61) | .33 |
Dimerized plasmin fragment D, median (IQR), ng/L | 845 (498-1551)b | 1282 (635-2123)b | <.001 |
Hematocrit, % | 39.2 (5.7) | 37.7 (7.0) | <.001 |
Hemoglobin, g/dL | 13.0 (2.0) | 12.2 (2.4) | <.001 |
Mean corpuscular hemoglobin, pg/cell | 29.0 (2.5) | 29.3 (2.7) | .04 |
Mean corpuscular hemoglobin concentration, g/dL | 33.1 (1.4) | 32.4 (1.6) | <.001 |
Platelet count, 103/μL | 216.8 (92.4) | 185.4 (90.4) | <.001 |
Red blood cell count, 106/μL | 4.5 (0.7) | 4.2 (0.9) | <.001 |
White blood cell count, 103/μL | 7.4 (6.3) | 8.1 (4.3) | .05 |
Other outcomes | |||
Length of hospital stay, d | 16.7 (15.5) | 11.8 (11) | <.001 |
Comorbidities, % | |||
Any | 37 | 54 | <.001 |
COPD | 4 | 13 | <.001 |
Diabetes | 17 | 22 | .04 |
Hypertension | 23 | 36 | <.001 |
Coronary artery disease | 8 | 16 | <.001 |
Chronic kidney disease | 8 | 21 | <.001 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); COPD, chronic obstructive pulmonary disease; IQR, interquartile range; RDW, red blood cell distribution width.
SI conversion: To convert dimerized plasmin fragment D level to nmol/L, multiply by 0.005476; to convert platelet count to ×109/L, multiply by 1.0; to convert red blood cell count to ×1012/L, multiply by 1.0; to convert white blood cell count to ×109/L, multiply by 0.001.
Statistical significance was calculated using a 2-sided t test for means, a χ2 test for percentages, and 2-sided Wilcoxon rank sum test for dimerized plasmin fragment D.
Dimerized plasmin fragment D is presented as median IQR because of its long upper tail.