TABLE 3.
Results obtained by each test
| Parameter | Value [no. with result/total no. tested (%) or as indicated] for: |
||
|---|---|---|---|
| QFT ELISA | IP-10 ELISA | IP-10 qPCR | |
| Cutoff | 0.35 IU/ml | 0.83 ng/ml | 16-fold change |
| AUC | 0.99 | 0.98 | 0.97 |
| TB patients (n = 89) | |||
| Positive | 80/89 (90) | 77/89 (87) | 71/89 (80) |
| Negative | 9/89 (10) | 12/89 (13) | 18/89 (20) |
| Indeterminatea | 0/89 (0) | 0/89 (0) | |
| Controls (n = 99) | |||
| Positive | 0/99 (0) | 2/99 (2) | 2/99 (2) |
| Negative | 99/99 (100) | 97/99 (98) | 97/99 (98) |
| Indeterminate | 0/99 (0) | 0/99 (0) | |
a
Indeterminate for IP-10 ELISA was set to mitogen minus nil of <0.5 ng/ml. Indeterminate for IP-10 qPCR was not applied due to assay setup.