Table 1.
Recapitulation of the attractors of the iron regulatory network of Figure 5, for the parallel updating mode, with the list of expressed (in state 1) and not expressed (in state 0) genes and their relative attraction basin sizes, obtained by simulating in parallel updating mode a threshold Boolean network having a constant absolute value of non zero weights equal to one and a threshold equal to zero, from all the possible initial configurations.
Order | Gene | Fixed Point | Fixed Point 2 | Limit-Cycle 1 | Limit-Cycle 2 | |||
---|---|---|---|---|---|---|---|---|
1 | TfR1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
2 | FPN1a | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3 | C-Myc | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
4 | Notch | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
5 | GATA-3 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
6 | IRP | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
7 | Ft | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
8 | Fe | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
9 | MiR-485 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
10 | CiRs-7 anti-sense | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relative Attraction Basin Size | 512/1024 | 256/1024 | 216/1024 | 40/1024 |