Figure 2.

The kinetic scheme for the five-state NAC with selection. The cognate (right) and non-cognate (wrong) nucleotide species are differentiated into two NAC pathways, and one uses a population vector $II={(P_I,P_{II},P_{III}^r,P_{III}^w,P_{IV}^r,P_{IV}^w,P_V^r,P_V^w)}^T$ to describe the state probability distributions.