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. 2020 Aug 11;45(10):792–798. doi: 10.1136/rapm-2020-101361

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© American Society of Regional Anesthesia & Pain Medicine 2020. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, an indication of whether changes were made, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Probe placement and Study Design. (A) The probe tip was placed directly under the sciatic nerve (parallel placement for TRF and angle independent for CRF) using visual guidance. (B) Cohort 1 included rats that were distributed into two treatment groups for same-day immunohistochemistry (IHC) analysis, using clinical run parameters (C) Cohort 2 included a group of rats that were survived for 12 weeks for EMG analysis and another group that was survived for 4 weeks for MRI analysis. CRF, cooled radiofrequency; EMG, electromyography; RFA, radiofrequency ablation; TRF, traditional radiofrequency.