Table 5.

Differences in cardiometabolic parameters between both groups at different time points. All data are reported as mean (95% CI)

	Total Cholesterol (mg/dl)			HDL Cholesterol (mg/dl)			Fasting blood glucose (mg/dl)
	Ketogenic	Low-GI Nutrigenetic	P	Ketogenic	Low-GI Nutrigenetic	P	Ketogenic	Low-GI Nutrigenetic	P
Baseline	245.6 (234.8–256.5)	242.0 (235.0–249.0)	0.56	45.1 (43.4–46.8)	47.6 (46.4–48.8)	0.16	120.5 (119.4–121.5)	105.7 (103.5–108.0)	< 0.0001
24 weeks	185.8 (181.4–190.2)	210.3 (205.5–215.0)	< 0.0001	54.1 (52.8–55.4)	55.2 (54.3–56.0)	0.182	98.2 (96.7–99.5)	87.0 (85.6–88.3)	< 0.0001
2 years	210.2 (204.7–215.7)	189.4 (187.7–191.1)	< 0.0001	49.8 (48.8–50.9)	59.5 (59.1–60.0)	< 0.0001	106.8 (104.4–109.1)	81.1 (80.2–81.8)	< 0.0001
Mean % Change at 2 years from baseline	− 13.0% (− 16.0 to − 10.0%)	−20.9% (− 22.8 to − 19.0%)	< 0.0001	11.6% (8.7–14.5%)	26.1% (23.3–29.1%)	< 0.0001	−11.3% (− 13.2 to − 9.4%)	−22.9% (− 24.3 to − 21.7%)	< 0.0001

Data were analysed using ANCOVA, with significance set at p < 0.05 for primary observations and p < 0.001 for secondary observations