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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: J Am Coll Cardiol. 2020 Jul 28;76(4):357–370. doi: 10.1016/j.jacc.2020.05.057

Table 1.

Baseline characteristics for the entire cohort and in relationship to detectable and undetectable hs-cTnT and CAC.

Total n=6749 CAC Hs-cTnT CAC and hs-cTnT
CAC=0 n=3379 (50%)) CAC>0 N=3370 (50%) P value <LoD n=2150 (32%) ≥LoD n=4599 (68%) P value Hs-cTnT <LoD and CAC=0 n=1480 (22%) Hs-cTnT ≥LoD and CAC=0 n=1899 (28%) Hs-cTnT <LoD and CAC >0 n=670 (10%) Hs-cTnT ≥LoD and CAC >0 n=2700 (40%) P value
Age, mean(SD) 62 (10) 58 (9) 66 (10) <0.0001 57 (9) 65 (10) <0.0001 55 (8) 60 (10) 61 (9) 68 (9) <0.0001
Women, n (%) 3563 (53) 2141 (63) 1422 (42) <0.0001 1591 (74) 1972 (43) <0.0001 1152 (78) 989 (52) 439 (66) 983 (36) <0.0001
Race/ethnicity <0.0001 <0.0001 <0.0001
 White, n (%) 2602 (3939) 1117 (3333) 1485 (44) - 741 (3535) 1861 (4141) - 488 (3333) 629 (3333) 253 (3838) 1232 (46) -
 Chinese, n (%) 798 (1212) 396 (1212) 402 (1212) - 330 (1515) 468 (1010) - 204 (1414) 192 (1010) 126 (1919) 276 (1010) -
 Black, n (%) 1864 (2828) 1053 (3131) 811 (2424) - 565 (2626) 1299 (2828) - 408 (2828) 645 (3434) 157 (2323) 654 (2424) -
 Hispanic, (%) 1485 (2222) 813 (2424) 672 (2020) - 514 (2424) 971 (2121) - 380 (2626) 433 (2323) 134 (2020) 538 (2020) -
Never smoked, n (%) 3388 (50) 1886 (56) 1502 (45) <0.0001 1196 (56) 2192 (48) <0.0001 880 (60) 1006 (53) 316 (47) 1186 (44) <0.0001
Body mass index, mean (SD) 28.3 (5.5) 28 (66) 28 (55) 0.17 27.9 (5.7) 28.5 (5.4) <0.0001 28 (66) 29 (66) 28 (66) 29 (55) <0.0001
Physical activity (MET-min/week) 5754 (5894) 6012 (5808) 5496 (5968) <0.0001 5827 (5380) 5720 (6119) 0.001 5907 (5337) 6093 (6150) 5650 (5475) 5457 (6085) <0.0001
Diabetes, n (%) 844 (1313) 311 (99) 533 (1616) <0.0001 155 (7.2) 689 (1515) <0.0001 86 (66) 225 (1212) 69 (1010) 464 (1717) <0.0001
Hypertension, n (%) 3028 (45) 1185 (3535) 1843 (55) <0.0001 649 (3030) 2379 (52) <0.0001 379 (2626) 806 (42) 270 (4040) 1573 (58) <0.0001
Systolic blood pressure (mmHg), mean (SD) 126.6 (2222) 122 (2020) 131 (2222) <0.0001 120.1 (2020) 129.6 (2222) <0.0001 118 (1919) 126 (2121) 125 (2020) 132 (2222) <0.0001
Diastolic blood pressure (mmHg), mean (SD) 71.9 (1010) 71 (1010) 73 (1010) <0.0001 70.0 (9.9) 72.8 (1010) <0.0001 70 (1010) 73 (1010) 71 (99) 73 (1010) <0.0001
Hypertension medication use, n (%) 2509 (3737) 971 (2929) 1538 (46) <0.0001 537 (2525) 1972 (43) <0.0001 317 (2121) 654 (3434) 220 (3232) 1318 (49) <0.0001
Total cholesterol (mg/dL), mean (SD) 194 (3636) 194 (3535) 195 (3636) 0.58 196 (3535) 193 (3636) 0.0021 195 (3535) 193 (3535) 198 (3535) 194 (3737) 0.003
LDL cholesterol (mg/dL), mean (SD) 117 (3131) 115.9 (3131) 118.4 (3232) 0.008 118 (3232) 117 (3131) 0.27 117 (3131) 115 (3131) 121 (3333) 118 (3232) 0.007
HDL cholesterol (md/dL), mean (SD) 51 (1515) 52.5 (1515) 49.4 (1515) <0.0001 53 (1515) 50 (1515) <0.0001 54 (1515) 51 (1515) 51 (1414) 49 (1515) <0.0001
Triglycerides (mg/dL), mean (SD) 132 (88) 127 (85) 136 (92) <0.0001 126 (80) 134 (93) 0.0002 122 (73) 131 (94) 134 (93) 137 (92) <0.0001
Lipid-lowering medication use,
n (%)
1098 (1616) 360 (1111) 738 (2222) <0.0001 258 (1212) 840 (1818) <0.0001 128 (99) 232 (1212) 130 (1919) 608 (2323) <0.0001
Any coronary artery calcium present, n (%) 3370 (50) <0.0001 670 (3131) 2700 (59) <0.0001 0 (0) 0 (0) 146 (292) 327 (594)
Coronary artery calcium, mean (SD) 145 (416) 0 (0) 291 (552) <0.0001 45 (176) 192 (483) <0.0001 <0.0001
Coronary artery calcium score - <0.0001 1480(100) 1899(100) 0 (0) 0 (0) -
 Coronary artery calcium score, 0, n (%) 3379 (50) 3379 (100 ) 0 (0.0) 1480 (69) 1899 (4141) 0 (0) 0 (0) 453 (68) 1331 (49)
 Coronary artery calcium score, 1-99, n (%) 1784 (2626) 0 (0.0) 1784 (53) 453 (2121) 1331 (2929) 0 (0) 0 (0) 217 (3232) 1369 (51)
 Coronary artery calcium score >100, n (%) 1586 (2424) 0 (0.0) 1586 (47) 217 (1010) 1369 (3030)