Table 2.
ASCVD event rates in relationship to detectable and undetectable hs-cTnT and CAC for the entire cohort and by sex.
| CAC | Hs-cTnT | CAC and hs-cTnT | ||||||
|---|---|---|---|---|---|---|---|---|
| CAC=0 | CAC>0 | <LoD | ≥LoD | Hs-cTnT <LoD and CAC=0 | Hs-cTnT ≥LoD and CAC=0 | Hs-cTnT <LoD and CAC >0 | Hs-cTnT ≥LoD and CAC >0 | |
| Overall cohort | ||||||||
| Total (n) | 3379 | 3370 | 2150 | 4599 | 1480 | 1899 | 670 | 2700 |
| ASCVD events (n) | 228 | 774 | 150 | 852 | 57 | 171 | 93 | 681 |
| Total-person-years | 45721 | 38491 | 28791 | 55422 | 20418 | 25304 | 8373 | 30118 |
| Crude CVD rate per 1,000 person-years | 5.0 | 20.1 | 5.2 | 15.4 | 2.8 | 6.8 | 11.1 | 22.6 |
| 10-year proportion with ASCVD (%) (95% CI) | 3.6 (3.0-4.3) | 17.5 (16.1-18.8) | 4.7 (3.7-5.6) | 13.2 (12.2-14.2) | 2.4 (1.6-3.2) | 4.6 (3.6-5.5) | 9.8 (7.5-12.2) | 19.4 (17.8-21.0) |
| Male | ||||||||
| Total (n) | 1238 | 1948 | 559 | 2627 | 328 | 910 | 231 | 1717 |
| ASCVD events (n) | 100 | 496 | 54 | 542 | 15 | 85 | 39 | 457 |
| Total-person-years | 16539 | 21846 | 7373 | 31011 | 4520 | 12019 | 2854 | 18992 |
| Crude CVD rate per 1,000 person-years | 6.0 | 22.7 | 7.3 | 17.5 | 3.3 | 7.1 | 13.7 | 24.1 |
| 10-year proportion with ASCVD (%) (95% CI) | 4.1 (3.0-5.3) | 19.5 (17.6-21.3) | 6.0 (4.0-8.0) | 15.0 (13.6-16.4) | 2.0 (0.4-3.5) | 4.9 (3.4-.6.3) | 11.9 (7.5-16.1) | 20.6 (18.5-22.6) |
| Female | ||||||||
| Total (n) | 2141 | 1422 | 1591 | 1972 | 1152 | 989 | 439 | 983 |
| ASCVD events (n) | 128 | 278 | 96 | 310 | 42 | 86 | 54 | 224 |
| T otal-person-years | 29183 | 16646 | 21417 | 24411 | 15898 | 13284 | 5519 | 11127 |
| Crude CVD rate per 1,000 person-years | 4.4 | 16.7 | 4.5 | 12.7 | 2.6 | 6.5 | 9.8 | 20.1 |
| 10-year proportion with ASCVD (%) (95% CI) | 3.3 (2.5-4.1) | 14.7 (12.8-16.7) | 4.5 (3.2-5.2) | 10.7 (9.3-12.1) | 2.5 (1.6-3.4) | 4.3 (3.0-5.6) | 8.8 (6.011.5) | 17.4 (14.9-19.9) |