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. 2020 Sep 23;10(9):e039600. doi: 10.1136/bmjopen-2020-039600

Table 4.

Cox regression analysis for all stroke and ischaemic stroke

Univariable Multivariable analysis model 1 Multivariable analysis model 2
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Stroke
 Sinus rhythm 1 1 1
 Paroxysmal AF 2.194 (1.343–3.585) 0.002 1.837 (1.117–3.021) 0.017 1.972 (1.162–3.346) 0.012
 Persistent AF 8.297 (4.320–15.935) <0.001 5.804 (2.986–11.280) <0.001 5.160 (2.242–11.873) <0.001
Ischaemic stroke
 Sinus rhythm 1 1 1
 Paroxysmal AF 2.543 (1.502–4.305) 0.001 2.167 (1.270–3.700) 0.005 2.209 (1.248–3.910) 0.006
 Persistent AF 6.105 (2.655–14.040) <0.001 4.396 (1.887–10.243) 0.001 4.498 (1.713–11.812) 0.002

Multivariable analysis model 1: adjusted for age and sex; multivariable analysis model 2: adjusted for age, sex, body mass index, diabetes, hypertension, previous stroke, pro-brain natriuretic peptide, creatinine, ST-elevation myocardial infarction and warfarin.

AF, atrial fibrillation.