Table III.
Factors associated with deterioration of renal function one week after THA
| Descriptor | Deterioration of renal function N=14 | No deterioration of renal function N=189 | Univariate P value | Multivariate Odds Ratio | 95% Confidence Interval | P value |
|---|---|---|---|---|---|---|
| Gender (Male, Female) | 4, 10 | 30, 159 | 0.22 | 0.479 | 0.102-2.259 | 0.352 |
| Age (years) (mean±SD, range) | 69.2±8.1, 54-84 | 65.0±11.0, 37-90 | 0.164 | 1.054 | 0.991-1.121 | 0.097 |
| BMI (kg/m2) | 24.6±4.1, | 24.3±4.1, | ||||
| (mean±SD, range) | 16.8-30.5 | 16.0-42.7 | 0.748 | |||
| Pre-operative NSAIDs use | ||||||
| Yes | 7 (50%) | 48 (25%) | 0.046 | 5.014 | 1.187-21.174 | 0.028 |
| No | 7 (50%) | 141 (75%) | ||||
| Pre-operative ACEi/ARB use | ||||||
| Yes | 5 (36%) | 45 (24%) | 0.318 | |||
| No | 9 (64%) | 144 (76%) | ||||
| Pre-operative diuretics use | ||||||
| Yes | 1 (7%) | 7 (4%) | 0.523 | |||
| No | 13 (93%) | 182 (96%) | ||||
| Pre-operative statin use | ||||||
| Yes | 3 (21%) | 36 (19%) | 0.827 | |||
| No | 11 (79%) | 153 (81%) | ||||
| History of diabetes mellitus | ||||||
| Yes | 4 (29%) | 16 (8%) | 0.015 | 7.106 | 1.332-37.916 | 0.022 |
| No | 10 (71%) | 173 (92%) | ||||
| Pre-operative eGFR | 89.8±26.1, | 89.8±9.7, 43-90 | 0.07 | 1.057 | 1.023-1.093 | 0.001 |
| 53.3-142.4 | ||||||
| Post-operative NSAIDs use | ||||||
| Yes | 14 (100%) | 180 (95%) | 0.404 | |||
| No | 0 (0%) | 9 (5%) | ||||
| Operation time (min) | 56.1±25.0, 30-120 | 48.7±9.7, 43-90 | 0.162 | 1.007 | 0.984-1.031 | 0.543 |
| (mean±SD, range) | ||||||
| Total blood loss (g) | 287±143, 617-77 | 293±9.7, 43-90 | 0.885 | |||
| (mean±SD, range) | ||||||
| Anaesthetic type | ||||||
| Spinal | 12 (86%) | 183 (97%) | 0.039 | 3.456 | 0.390-30.654 | 0.265 |
| General | 2 (14%) | 6 (3%) |
*THA, total hip arthroplasty; SD, standard deviation; BMI, body mass index; NSAIDs, nonsteroidal anti-inflammatory drugs; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin-II receptor blocker; eGFR, estimated glemerular filtration rate.