TABLE 1.
Top ten enriched GO terms in predicted ASD risk genes.
| GO terms | OR | 95%_CI_L | 95%_CI_U | p | padj |
| GO_CENTRAL_NERVOUS_SYSTEM_PROJECTION_NEURON_AXONOGENESIS | 27.0 | 10.0 | 80.1 | 1.7E-11 | 4.7E-08 |
| GO_IONOTROPIC_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | 17.5 | 6.9 | 45.3 | 1.9E-09 | 5.1E-06 |
| GO_CENTRAL_NERVOUS_SYSTEM_NEURON_AXONOGENESIS | 17.2 | 7.1 | 42.5 | 4.3E-10 | 1.2E-06 |
| GO_DENDRITE_MORPHOGENESIS | 13.0 | 6.2 | 27.0 | 6.5E-11 | 1.8E-07 |
| GO_MOTOR_NEURON_AXON_GUIDANCE | 11.2 | 4.4 | 27.6 | 6.7E-07 | 0.0018 |
| GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION | 11.1 | 5.0 | 24.4 | 1.4E-08 | 4.0E-05 |
| GO_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | 11.1 | 5.4 | 22.4 | 3.1E-10 | 8.7E-07 |
| GO_EXCITATORY_POSTSYNAPTIC_POTENTIAL | 10.4 | 4.1 | 25.2 | 1.1E-06 | 0.003 |
| GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION | 10.4 | 4.1 | 25.2 | 1.1E-06 | 0.003 |
| GO_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | 9.3 | 3.6 | 23.2 | 7.1E-06 | 0.019 |
OR: odds ratio; 95%_CI_L: OR 95% confidence interval lower bound; 95%_CI_U: OR 95% confidence interval upper bound.