Table II.
Complications and treatments of COVID-19 patients with and without CRS before and after propensity score matching
Complications and treatments | Unmatched |
Matched (1:1)† |
|||||
---|---|---|---|---|---|---|---|
Without CRS N = 1100 |
With CRS N = 72 |
P value | Adjusted P value∗ | Without CRS N = 72 |
With CRS N = 72 |
P value | |
Complications, N (%) | |||||||
Acute liver injury | 74 (6.7) | 5 (6.9) | .81 | .43 | 6 (8.3) | 5 (6.9) | .75 |
ARDS | 66 (6.0) | 4 (5.6) | .88 | .79 | 4 (5.6) | 4 (5.6) | .99 |
Acute kidney injury | 61 (5.5) | 2 (2.8) | .42 | .24 | 4 (5.6) | 2 (2.8) | .40 |
Acute myocardial injury | 29 (2.6) | 2 (2.8) | .72 | .88 | 1 (1.4) | 2 (2.8) | .56 |
Shock | 7 (0.6) | 2 (2.8) | .10 | .17 | 0 (0) | 2 (2.8) | .15 |
In-hospital treatments, N (%) | |||||||
Antiviral treatment | 1027 (93.4) | 65 (90.3) | .31 | .30 | 68 (94.4) | 65 (90.3) | .35 |
Antibiotic treatment | 799 (72.6) | 51 (70.8) | .73 | .55 | 49 (68.1) | 51 (70.8) | .72 |
Oxygen supplementation | 871 (79.2) | 58 (80.6) | .78 | .79 | 57 (79.2) | 58 (80.6) | .84 |
Mechanical ventilation | 43 (3.9) | 2 (2.8) | .62 | .61 | 2 (2.8) | 2 (2.8) | .99 |
Glucocorticoid therapy | 281 (25.5) | 14 (19.4) | .25 | .15 | 16 (22.2) | 14 (19.4) | .68 |
Intravenous immunoglobulin therapy | 177 (16.1) | 12 (16.7) | .90 | .94 | 14 (19.4) | 12 (16.7) | .66 |
ARDS, Acute respiratory distress syndrome; COVID-19, coronavirus disease 2019; CRS, chronic rhinosinusitis.
Data are presented as numbers with percentage for categorical variables.
The χ2 or Fisher's exact test was applied to compare the difference in proportions between groups.
In adjusted logistic regression analysis, adjusted variables included age, gender, smoking, and comorbidities (hypertension, diabetes, cardiovascular disease, cerebrovascular diseases, malignancy, chronic liver diseases, chronic kidney diseases, allergic rhinitis, asthma, and chronic obstructive pulmonary disease).
Age, gender, smoking status, and comorbidities were selected for propensity score matching. Please see Table I.