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. 2020 Sep 24;289:198170. doi: 10.1016/j.virusres.2020.198170

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© 2020 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 1 — Visual example of the analytical method used in mutant evaluation. Screenshot of the 28,840 nucleotide (nt.)-28,920 nt. segment from the SARS-CoV-2 nucleotide sequence of different samples from Europe and the US. DNA sequences were aligned with the GGG → AAC mutation at position 28,881 nt. For DNA alignments the program Vector NTI Advance 11.0 Tool Align X was used. The top row presents the sequence of the original 2019 Wuhan, China isolate (NC_045512.2) which served as the reference for all sequence comparisons.