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TGF-β promotes tumorigenicity in vivo. (a and b) Representative images of the xenograft tumors formed in nude mice injected with siRNA targeting TGF-β (si-TGF-β) or control siRNA (si-control). The volumes and weights of xenograft tumors are summarized. (c) Representative images of immunohistochemical staining for Ki-67, p-PI3K, and p-Akt in tumor nodules.
